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Literature summary for 3.1.3.11 extracted from
- Purification and properties of fructose 1,6-bisphosphatase from turkey liver (1975), Arch. Biochem. Biophys., 168, 171-179.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | activation | Meleagris gallopavo |  |
| His | activation | Meleagris gallopavo | |
| His | D-His and L-His activate equally | Meleagris gallopavo | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AMP | sensitivity to AMP is decreased with increase in pH, temperature and Mg2+ concentration | Meleagris gallopavo | |
| fructose 1,6-diphosphate | above 0.015 mM | Meleagris gallopavo | |
| Mg2+ | above 1.5 mM | Meleagris gallopavo | |
| Mn2+ | above 0.075 mM | Meleagris gallopavo | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | optimal concentration: 1-1.5 mM | Meleagris gallopavo | |
| Mg2+ | divalent cation required. Mn2+ or Mg2+ | Meleagris gallopavo | |
| Mn2+ | divalent cation required. Mn2+ or Mg2+ | Meleagris gallopavo | |
| Mn2+ | Mn2+ is significantly more effective than Mg2+ | Meleagris gallopavo | |
| Mn2+ | optimal concentration: 0.05-0.075 mM | Meleagris gallopavo | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Meleagris gallopavo | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Meleagris gallopavo |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Meleagris gallopavo | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 6.9 | - |
pH 9.2 | Meleagris gallopavo |
| 18.05 | - |
pH 7.5 | Meleagris gallopavo |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose 1,6-diphosphate + H2O | - |
Meleagris gallopavo | D-fructose 6-phosphate + phosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.3 | 7.7 | in presence of His, at 42°C | Meleagris gallopavo |
| 7.5 | 7.7 | in presence of His, at 30°C | Meleagris gallopavo |
| 8.3 | 8.5 | at 30°C and at 42°C | Meleagris gallopavo |
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Release 2023.1 (January 2023)
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