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Literature summary for 3.1.3.11 extracted from
- Fructose-1,6-bisphosphatase from bumblebee flight muscle (1982), Methods Enzymol., 90, 366-371.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| oleate | activates | Bombus terrestris |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AMP | no inhibition | Bombus terrestris | |
| Ca2+ | inhibition is potentiated by Li+ | Bombus terrestris | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
fructose 1,6-diphosphate | activated by Mn2+ | Bombus terrestris | |
| 0.011 | - |
fructose 1,6-diphosphate | activated by Mg2+ | Bombus terrestris | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | Km: 0.2 mM | Bombus terrestris | |
| Mg2+ | activates | Bombus terrestris | |
| Mn2+ | activates | Bombus terrestris | |
| Mn2+ | Km: 0.03 mM | Bombus terrestris | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 142000 | - |
- |
Bombus terrestris |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose 1,6-diphosphate + H2O | Bombus terrestris | the enzyme is involved in the futile cycling of fructose 6-phosphate and fructose 1,6-diphosphate in flight muscle, the net result of which is the hydrolysis of ATP | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bombus terrestris | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | flight muscle | Bombus terrestris | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Bombus terrestris |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose 1,6-diphosphate + H2O | the enzyme is involved in the futile cycling of fructose 6-phosphate and fructose 1,6-diphosphate in flight muscle, the net result of which is the hydrolysis of ATP | Bombus terrestris | ? | - |
? | |
| D-fructose 1,6-diphosphate + H2O | - |
Bombus terrestris | D-fructose 6-phosphate + phosphate | - |
? | |
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