Literature summary for 3.1.3.1 extracted from

Numa-Kinjoh, N.; Komaru, K.; Ishida, Y.; Sohda, M.; Oda, K.
Molecular phenotype of tissue-nonspecific alkaline phosphatase with a proline (108) to leucine substitution associated with dominant odontohypophosphatasia (2015), Mol. Genet. Metab., 115, 180-185 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Tet-On CHO cells	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
P108L	inactive, the mutation is associated with dominant odontohypophosphatasia	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P05186	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-nitrophenyl phosphate + H2O	-	Homo sapiens	4-nitrophenol + phosphate	-	?
alpha-naphthyl phosphate + H2O	-	Homo sapiens	alpha-naphthol + phosphate	-	?

Subunits

Subunits	Comment	Organism
homodimer	2 * 80000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
ALP	-	Homo sapiens
tissue-nonspecific alkaline phosphatase	-	Homo sapiens
TNSALP	-	Homo sapiens

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Release 2023.1 (January 2023)