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Literature summary for 3.1.3.1 extracted from
- Alkaline phosphatase inhibition by vanadyl-beta-diketone complexes: electron density effects (2009), J. Enzyme Inhib. Med. Chem., 24, 22-28.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| bis(1,1,1-trifluoroacetylacetonato)oxovanadium(IV) | - |
Bos taurus |  |
| bis(3-chloroacetylacetonato)oxovanadium(IV) | - |
Bos taurus | |
| bis(3-chloroacetylacetonato)oxovanadium(IV)(4-Mepy) | - |
Bos taurus | |
| bis(3-methylacetylacetonato)oxovanadium(IV) | - |
Bos taurus | |
| bis(acetylacetonato)oxovanadium(IV) | - |
Bos taurus | |
| bis(acetylacetonato)oxovanadium(IV)(4-Mepy) | - |
Bos taurus | |
| bis(benzoylacetonato)oxovanadium(IV) | - |
Bos taurus | |
| Na3VO4 | - |
Bos taurus | |
| VOSO4 | - |
Bos taurus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl phosphate + H2O | - |
Bos taurus | 4-nitrophenol + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alkaline phosphatase | - |
Bos taurus |
| APase | - |
Bos taurus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Bos taurus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00007 | - |
bis(1,1,1-trifluoroacetylacetonato)oxovanadium(IV) | pH 8, 37°C | Bos taurus | |
| 0.00015 | - |
bis(3-chloroacetylacetonato)oxovanadium(IV) | pH 8, 37°C | Bos taurus | |
| 0.00034 | - |
bis(3-methylacetylacetonato)oxovanadium(IV) | pH 8, 37°C | Bos taurus | |
| 0.0004 | - |
bis(benzoylacetonato)oxovanadium(IV) | pH 8, 37°C | Bos taurus | |
| 0.00043 | - |
bis(acetylacetonato)oxovanadium(IV) | pH 8, 37°C | Bos taurus | |
| 0.00049 | - |
Na3VO4 | pH 8, 37°C | Bos taurus | |
| 0.00055 | - |
VOSO4 | pH 8, 37°C | Bos taurus | |
| 0.00069 | - |
bis(acetylacetonato)oxovanadium(IV)(4-Mepy) | pH 8, 37°C | Bos taurus | |
| 0.00104 | - |
bis(3-chloroacetylacetonato)oxovanadium(IV)(4-Mepy) | pH 8, 37°C | Bos taurus | |
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Release 2023.1 (January 2023)
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