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Literature summary for 3.1.3.1 extracted from
- Establishment and characterization of tartrate-resistant acid phosphatase and alkaline phosphatase double positive cell lines (2001), Cell Tissue Res., 304, 351-359.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | CCP-2 cells are an important tool for investigation of chondrooclastogenesis/osteoclastogenesis and endochondrial ossification | Cricetulus griseus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | tartrate-rsistant | Cricetulus griseus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Cricetulus griseus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cricetulus griseus | - |
Syrian hamster | - |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| a phosphate monoester + H2O = an alcohol + phosphate | Wide specificity. Also catalyses transphosphorylations. Some enzymes hydrolyse diphosphate | Cricetulus griseus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| bone marrow | cell culture | Cricetulus griseus | - |
| cartilage | humeral epiphyseal from 14-days-old hamsters | Cricetulus griseus | - |
| CCP-2 cell | morphologically macrophage-like cells cloned from bone marrow cells by coculturing bone marrow cells with chondrocytes, the CCP-2 cells are similar to osteoclast but not the same | Cricetulus griseus | - |
| chondrocyte | hypertrophic | Cricetulus griseus | - |
| additional information | located at the secondary ossification site of hamster humerus | Cricetulus griseus | - |
| osteoblast | cell surface | Cricetulus griseus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl phosphate + H2O | - |
Cricetulus griseus | 4-nitrophenol + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alkaline phosphatase | - |
Cricetulus griseus |
| ALP | - |
Cricetulus griseus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Cricetulus griseus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9.5 | - |
assay at | Cricetulus griseus |
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Release 2023.1 (January 2023)
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