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Literature summary for 3.1.26.8 extracted from
- The 5S rRNA maturase, ribonuclease M5, is a Toprim domain family member (2005), Nucleic Acids Res., 33, 4368-4376.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D14A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| D56A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| D58A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| E10A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| G11A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| G31A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| G61A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| I52A | 60% of wild-type activity | Geobacillus stearothermophilus |
| I64A | as active as wild-type enzyme | Geobacillus stearothermophilus |
| L107A | less than 10% of wild-type activity | Geobacillus stearothermophilus |
| L162A | about 25% of wild-type activity | Geobacillus stearothermophilus |
| R65A | about 10% of wild-type activity | Geobacillus stearothermophilus |
| Y152A | as active as wild-type enzyme | Geobacillus stearothermophilus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5S precursor rRNA + H2O | Geobacillus stearothermophilus | 5S rRNA maturation | mature 5S rRNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacillus stearothermophilus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| RNase M5 mutant enzymes | Geobacillus stearothermophilus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5S precursor rRNA + H2O | - |
Geobacillus stearothermophilus | mature 5S rRNA | - |
? | |
| 5S precursor rRNA + H2O | 5S rRNA maturation | Geobacillus stearothermophilus | mature 5S rRNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ribonuclease M5 | - |
Geobacillus stearothermophilus |
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Release 2023.1 (January 2023)
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