Literature summary for 3.1.26.8 extracted from

Meyhack, B.; Pace, B.; Pace, N.R.
Involvement of precursor-specific segments in the in vitro maturation of Bacillus subtilis precursor 5S ribosomal RNA (1977), Biochemistry, 16, 5009-5015.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5S rRNA precursor + H2O	the enzyme cleaves twice in double-helical region of a 179-nucleotide precursor of 5S rRNA to yield mature 5S rRNA of 116 nucleotides plus fragments of 21 and 42 nucleotides. The conformation, not sequence, is the important feature in the locale of the cleaved bonds	Bacillus subtilis	mature 5S rRNA + oligonucleotides	-	?
5S rRNA precursor + H2O	the 5'-precursor-specific segment contains one or more components recognized by RNase M5 during its interaction with the p5A substrate	Bacillus subtilis	mature 5S rRNA + oligonucleotides	-	?
additional information	the artificial substrate lacking the 5'-terminal precursor segment is cleaved very much more slowly than that lacking 3' segment	Bacillus subtilis	?	-	?

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Release 2023.1 (January 2023)