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Literature summary for 3.1.26.8 extracted from

  • Meyhack, B.; Pace, N.R.
    Involvement of the mature domain in the in vitro maturation of Bacillus subtilis precursor 5S ribosomal RNA (1978), Biochemistry, 17, 5804-5810.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5S rRNA precursor + H2O recognition elements in potential RNase M5 substrates mainly reside in the mature moiety of the precursor. The enzyme recognizes the overall conformation of potential substrates Bacillus subtilis mature 5S rRNA + oligonucleotides
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5S rRNA precursor + H2O the enzyme cleaves twice in double-helical region of a 179-nucleotide precursor of 5S rRNA to yield mature 5S rRNA of 116 nucleotides plus fragments of 21 and 42 nucleotides. The conformation, not sequence, is the important feature in the locale of the cleaved bonds Bacillus subtilis mature 5S rRNA + oligonucleotides
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