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Literature summary for 3.1.26.5 extracted from

  • Koutmou, K.S.; Casiano-Negroni, A.; Getz, M.M.; Pazicni, S.; Andrews, A.J.; Penner-Hahn, J.E.; Al-Hashimi, H.M.; Fierke, C.A.
    NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P (2010), Proc. Natl. Acad. Sci. USA, 107, 2479-2484.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ significant association of Mg2+ ions at the P4 major groove of RNase P near the flexible pivot point (A5, G22, and G23) Bacillus subtilis
Mn2+ Mn2+ paramagnetic line broadening experiments reveal strong metal localization at residues corresponding to G378 and G379 Bacillus subtilis
Zn2+ Zn2+ is involved in inner-sphere interactions with the P4 helix mimic of RNase P, the bound Zn2+ exhibits six-coordinate geometry with an average Zn2+-O/N bond distance of 2.08 A Bacillus subtilis

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-

Synonyms

Synonyms Comment Organism
ribonuclease P
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Bacillus subtilis
RNase P
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Bacillus subtilis