Literature summary for 3.1.26.5 extracted from

Schmidt, F.J.; Seidman, J.G.; Bock, R.M.
Transfer ribonucleic acid biosynthesis. Substrate specificity of ribonuclease P (1976), J. Biol. Chem., 251, 2440-2445.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Escherichia coli MRE 600	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
pre-tRNA precursor + H2O	the enzyme cleaves precursor RNA terminating in either CCA or UAA to generate the 5'-termini characteristic of both mature RNA species: Kinetically favors precursor RNA ending CCA over that ending UAA	Escherichia coli	tRNA + 5'-oligoribonucleotide	-	?
pre-tRNA precursor + H2O	the enzyme cleaves precursor RNA terminating in either CCA or UAA to generate the 5'-termini characteristic of both mature RNA species: Kinetically favors precursor RNA ending CCA over that ending UAA	Escherichia coli MRE 600	tRNA + 5'-oligoribonucleotide	-	?

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Release 2023.1 (January 2023)