Cloned (Comment) | Organism |
---|---|
gene rnc, rnc is carried on the chromosome, in a region dense with genes related to translation, two polycistronic transcripts | Borreliella burgdorferi |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of an rnc null mutant in Borrelia burgdorferi that exhibits a pleiotropic phenotype, including decreased growth rate and increased cell length. The chromosomal rncBb gene is replaced through homologous recombination with the gentamicin resistance cassette flgBp-aacC1. Mutant rncBb operon structure. The RNase III mutant is viable but has altered processing of rRNA, phenotype, overview | Borreliella burgdorferi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Borreliella burgdorferi | O51648 | strains B31-A3 and 297 (BbAH130) | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | cleavage of an artificial 23S rRNA stem-loop substrate by the wild-type enzyme. The sequence is composed of the double-stranded stem portion of the Borrelia burgdorferi 23S rRNA transcript with a loop of four unmatched nucleotides. Modelling for rRNA processing, overview | Borreliella burgdorferi | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BB_0705 | - |
Borreliella burgdorferi |
endoribonuclease III | - |
Borreliella burgdorferi |
RNase III | - |
Borreliella burgdorferi |
rnc | - |
Borreliella burgdorferi |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Borreliella burgdorferi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
assay at | Borreliella burgdorferi |
General Information | Comment | Organism |
---|---|---|
malfunction | a chromosomal rncBb gene exhibits a pleiotropic phenotype, including decreased growth rate and increased cell length. RNase III mutant is viable but has altered processing of rRNA, phenotype, overview | Borreliella burgdorferi |
physiological function | endoribonuclease III (RNase III) is involved in processing the 23S rRNA in Borrelia burgdorferi. The enzyme is RNase III required for the full maturation of the 23S rRNA but not for the 5S rRNA nor for the 16S rRNA. Several ribonucleases, including RNase III, are involved in the production of ribosomes. RNase III is not essential in Borrelia burgdorferi | Borreliella burgdorferi |