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Literature summary for 3.1.26.13 extracted from
- RNase H as gene modifier, driver of evolution and antiviral defense (2017), Front. Microbiol., 8, 1745 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | - |
HIV-1 | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | reverse transcriptase RT-RNase H domain structure compare to other RNases H (EC 3.1.13.2), overview | Human immunodeficiency virus 1 |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ribonuclease H | - |
Human immunodeficiency virus 1 |
| RNase H | - |
Human immunodeficiency virus 1 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| evolution | RNase H acts as gene modifier, driver of evolution and antiviral defense, overview | Human immunodeficiency virus 1 |
| physiological function | reverse transcriptase (RT) acts in concert with the RNase H catalyzing retroviral replication, the retroviral ribonuclease H (RNase H) in retrovirus particles is essential component for the replication of viral RNA via an RNA/DNA hybrid intermediate to double-stranded DNA. RNase H is a part of the reverse transcriptase (RT) in retroviruses. But the enzyme has its proper role, impact on evolution and importance for the degradation of nucleic acids in various biological processes | Human immunodeficiency virus 1 |
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