Inhibitors | Comment | Organism | Structure |
---|---|---|---|
F3284-8495 | specific inhibitor with low micromolar potency in vitro | Human immunodeficiency virus 1 | |
F3385-2581 | - |
Human immunodeficiency virus 1 | |
F3385-2588 | - |
Human immunodeficiency virus 1 | |
F3385-2590 | - |
Human immunodeficiency virus 1 |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
reverse transcriptase | - |
Human immunodeficiency virus 1 |
reverse transcriptase-associated ribonuclease H | - |
Human immunodeficiency virus 1 |
RNase H | - |
Human immunodeficiency virus 1 |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0004 | - |
10 mM Mg2+, at pH 8.0 and 37°C | Human immunodeficiency virus 1 | F3385-2590 | |
0.0007 | - |
10 mM Mg2+, at pH 8.0 and 37°C | Human immunodeficiency virus 1 | F3385-2588 | |
0.0008 | - |
1 mM Mg2+, at pH 7.4 and 37°C | Human immunodeficiency virus 1 | F3385-2590 | |
0.0011 | - |
10 mM Mg2+, at pH 8.0 and 37°C | Human immunodeficiency virus 1 | F3284-8495 | |
0.0019 | - |
10 mM Mg2+, at pH 8.0 and 37°C | Human immunodeficiency virus 1 | F3385-2581 | |
0.0021 | - |
1 mM Mg2+, at pH 7.4 and 37°C | Human immunodeficiency virus 1 | F3385-2588 | |
0.0022 | - |
1 mM Mg2+, at pH 7.4 and 37°C | Human immunodeficiency virus 1 | F3385-2581 | |
0.0048 | - |
1 mM Mg2+, at pH 7.4 and 37°C | Human immunodeficiency virus 1 | F3284-8495 |