Cloned (Comment) | Organism |
---|---|
overexpression | [Bacillus] caldotenax |
overexpression | Thermotoga maritima |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
[Bacillus] caldotenax | |
Mg2+ | - |
Thermotoga maritima |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
damaged DNA containing nucleotide cross-links + H2O | [Bacillus] caldotenax | initiation of nucleotide excision repair of DNA-polypeptide cross-links by the UvrABC nuclease | ? | - |
? | |
damaged DNA containing nucleotide cross-links + H2O | Thermotoga maritima | initiation of nucleotide excision repair of DNA-polypeptide cross-links by the UvrABC nuclease | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermotoga maritima | - |
- |
- |
[Bacillus] caldotenax | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Thermotoga maritima |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
damaged DNA containing nucleotide cross-links + H2O | initiation of nucleotide excision repair of DNA-polypeptide cross-links by the UvrABC nuclease | [Bacillus] caldotenax | ? | - |
? | |
damaged DNA containing nucleotide cross-links + H2O | initiation of nucleotide excision repair of DNA-polypeptide cross-links by the UvrABC nuclease | Thermotoga maritima | ? | - |
? | |
damaged DNA containing nucleotide cross-links + H2O | initiation of nucleotide excision repair of DNA-polypeptide cross-links by the UvrABC nuclease, engineering of DNA-peptide or DNA-protein cross-links via linkage at an acrolein-derived gamma-hydroxypropanodeoxyguanosine adduct and an apurinic/apyrimidinic site, the linked peptides are KWKK and KFHEKHHSHRGY, and the protein is the 16 kDa T4 pyrimidine dimer glycosylase/apurinic/apyrimidinic site lyase, incision at the eighth phosphodiester bond 5' of the lesion | [Bacillus] caldotenax | ? | - |
? | |
damaged DNA containing nucleotide cross-links + H2O | initiation of nucleotide excision repair of DNA-polypeptide cross-links by the UvrABC nuclease, engineering of DNA-peptide or DNA-protein cross-links via linkage at an acrolein-derived gamma-hydroxypropanodeoxyguanosine adduct and an apurinic/apyrimidinic site, the linked peptides are KWKK and KFHEKHHSHRGY, and the protein is the 16 kDa T4 pyrimidine dimer glycosylase/apurinic/apyrimidinic site lyase, incision at the eighth phosphodiester bond 5' of the lesion | Thermotoga maritima | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UvrA | - |
[Bacillus] caldotenax |
UvrABC nuclease | - |
[Bacillus] caldotenax |
UvrABC nuclease | - |
Thermotoga maritima |
UvrB | - |
[Bacillus] caldotenax |
UvrC | - |
Thermotoga maritima |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
assay at | [Bacillus] caldotenax |
55 | - |
assay at | Thermotoga maritima |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | [Bacillus] caldotenax |
7.5 | - |
assay at | Thermotoga maritima |