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Literature summary for 3.1.22.1 extracted from

  • Murai, K.; Yamanaka, M.; Akagi, K.; Anai, M.
    Purification and properties of deoxyribonuclease II from human urine (1980), J. Biochem., 87, 1097-1103.
    View publication on PubMed
Search for more literature for 3.1.22.1

Activating Compound

Activating Compound Comment Organism Structure
EDTA slight activation Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity by chromatography steps and isoelectric focusing Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
urine multiple isoforms Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.42 0.51
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O native DNA degraded 5-15 times faster than denatured DNA Homo sapiens 3'-phosphooligonucleotides + 5'-hydroxyoligonucleotides average chain length 11 to 15mers ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
60
-
 stable up to, 50% loss of activity after 10 min incubation at 65°C Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.1 5.3 in acetate buffer Homo sapiens