Literature summary for 3.1.21.8 extracted from

Carlson, K.; Lagerback, P.; Nystrom, A.C.
Bacteriophage T4 endonuclease II: concerted single-strand nicks yield double-strand cleavage (2004), Mol. Microbiol., 52, 1403-1411.

Search for more literature for 3.1.21.8

Organism

Organism	UniProt	Comment	Textmining
Tequatrovirus T4	P07059	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	EndoII nicks both strands simultaneously at an in vivo-favoured site but not at an in vitro-favoured site. The right-side conserved sequence element at in vivo-favoured sites is important for simultaneous nicking of both strands, generating double-strand cleavage. EndoII nicks the lower strand about 1.5fold faster than the upper strand. In addition, the upper and lower strands are nicked independently of each other, seldom resulting in double-strand cleavage	Tequatrovirus T4	?	-	?

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Release 2023.1 (January 2023)