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Literature summary for 3.1.21.7 extracted from
- Harnessing asymmetrical substrate recognition by thermostable EndoV to achieve balanced linear amplification in multiplexed SNP typing (2006), Biochem. Cell Biol., 84, 232-242.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | high pH, metal cofactor Mn2+, using excess enzyme, and/or solvents such as dimethyl sulfoxide and betaine, lead to cleavage of most mismatched DNA base pairs | Thermotoga maritima |
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | method of linear amplification of DNA, allows 100fold amplification of target molecules | Thermotoga maritima |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Thermotoga maritima | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | cleavage of unmodified duplex DNA | Thermotoga maritima | hydrolysed DNA | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| endonuclease V | - |
Thermotoga maritima |
| EndoV | - |
Thermotoga maritima |
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Release 2023.1 (January 2023)
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