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Literature summary for 3.1.21.5 extracted from

  • Handa, N.; Kobayashi, I.
    Type III restriction is alleviated by bacteriophage (RecE) homologous recombination function but enhanced by bacterial (RecBCD) function (2005), J. Bacteriol., 187, 7362-7373.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information type III restriction is enhanced by bacterial (RecBCD) function Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
additional information type III restriction is alleviated by bacteriophage (RecE) homologous recombination function Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA + H2O Escherichia coli action of type III restriction enzymes takes place on replicated or replicating DNA in VIVO and leaves daughter DNAs with breaks at nonallelic sites, that bacteriophage-mediated homologous recombinantion reconstitutes an intact DNA from them, and that REcBCD exonuclease blocks this repair by degradation from the restriction breaks specific double-stranded DNA fragments with terminal 5'-phosphate
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Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O
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Escherichia coli specific double-stranded DNA fragments with terminal 5'-phosphate
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?
DNA + H2O action of type III restriction enzymes takes place on replicated or replicating DNA in VIVO and leaves daughter DNAs with breaks at nonallelic sites, that bacteriophage-mediated homologous recombinantion reconstitutes an intact DNA from them, and that REcBCD exonuclease blocks this repair by degradation from the restriction breaks Escherichia coli specific double-stranded DNA fragments with terminal 5'-phosphate
-
?

Synonyms

Synonyms Comment Organism
EcoPI
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Escherichia coli