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Literature summary for 3.1.21.3 extracted from

  • Seidel, R.; van Noort, J.; van der Scheer, C.; Bloom, J.G.; Dekker, N.H.; Dutta, C.F.; Blundell, A.; Robinson, T.; Firman, K.; Dekker, C.
    Real-time observation of DNA translocation by the type I restriction modification enzyme EcoR124I (2004), Nat. Struct. Mol. Biol., 11, 838-843.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
duplex DNA + ATP the two motor subunits of Eco124I are independent motors that translocate along the helical pitch of the DNA. Dynamic termination and reinitiation of translocation activity is governed by disassembly and reassembly of the enzyme Escherichia coli double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate
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Synonyms

Synonyms Comment Organism
EcoR124I
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Escherichia coli
type I restriction modification enzyme
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Escherichia coli