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Literature summary for 3.1.21.10 extracted from
- Holliday junction-binding peptides inhibit distinct junction-processing enzymes (2005), Proc. Natl. Acad. Sci. USA, 102, 6867-6872.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| WRWYCR | inhibits junction cleavage | Escherichia coli |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | the enzyme binds to stacked-X junctions in the presence of cations, in the absence of cations the enzyme binds to square-planar junctions | Escherichia coli | |
| spermidine | - |
Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | holliday structure | Escherichia coli | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | DTT reverses interactions between the enzyme and Holliday junction | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RuvC junction resolvase | - |
Escherichia coli |
| RuvC resolvase | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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