Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
Homo sapiens | |
EGTA | inhibition at 1 mM | Homo sapiens | |
G-actin | 50% inhibition at 0.002 mg/ml | Homo sapiens | |
NaCl | decreasing activity with increasing ionic strength | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | secreted into urine | Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Homo sapiens | |
Co2+ | activation at 10 mM | Homo sapiens | |
Mg2+ | activation at 10 mM, 2fold activation, if 1 mM CaCl2 is added | Homo sapiens | |
Mn2+ | activation at 10 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
SDS-PAGE, gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
double-stranded DNA + H2O | Homo sapiens | - |
5'-phosphooligonucleotides + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | contains fucose, mannose, galactose, glucosamine, sialic acid | Homo sapiens |
Purification (Comment) | Organism |
---|---|
to homogeneity by 6step chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
urine | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
units defined as absorbance at 260 nm/ml assay solution | Homo sapiens |
additional information | - |
1683 units/mg protein | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | degrades native DNA 2times faster than denatured DNA | Homo sapiens | 5'-phosphooligonucleotides + ? | - |
? | |
double-stranded DNA + H2O | - |
Homo sapiens | 5'-phosphooligonucleotides + ? | - |
? | |
heat-denatured DNA + H2O | - |
Homo sapiens | 5'-phosphooligonucleotides + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 34000, SDS-PAGE | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
stable up to, more stable up to 60°C, if Ca2+ is present | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
in the presence of 10 mM MgCl2 | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
4.5 | 9.5 | - |
Homo sapiens |