Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.2.6 extracted from

  • James, A.M.; Hoogewijs, K.; Logan, A.; Hall, A.R.; Ding, S.; Fearnley, I.M.; Murphy, M.P.
    Non-enzymatic N-acetylation of lysine residues by acetylCoA often occurs via a proximal S-acetylated thiol intermediate sensitive to glyoxalase II (2017), Cell Rep., 18, 2105-2112 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-(2-hydroxyacyl)glutathione + H2O Homo sapiens
-
glutathione + a 2-hydroxycarboxylate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16775
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-(2-hydroxyacyl)glutathione + H2O
-
Homo sapiens glutathione + a 2-hydroxycarboxylate
-
?
S-acetylglutathione + H2O
-
Homo sapiens acetate + glutathione
-
?

Synonyms

Synonyms Comment Organism
Glo2
-
Homo sapiens
glyoxalase II
-
Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme limits lysine N-acetylation and N-succinylation of mitochondrial proteins Homo sapiens