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Literature summary for 3.1.2.6 extracted from

  • Vanithadevi, B.; Anuradha, C.
    Effect of rosmarinic acid on insulin sensitivity, glyoxalase system and oxidative events in liver of fructose-fed mice (2008), Int. J. Diab. Metab., 16, 35-44.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
additional information rosmarinic acid administration to fructose-fed mice brings the activity of glyoxalase II to near normal. Normalization of the glyoxalase system can be attributed to reduction in the formation of oxoaldehydes Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
fructose inactivation of the glyoxalase system (glyoxalase I and II) in fructose fed mice Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
Swiss albino male mice
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-D-lactoylglutathione + H2O
-
Mus musculus D-lactate + glutathione
-
?

Synonyms

Synonyms Comment Organism
glyoxalase II
-
Mus musculus