Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.2.6 extracted from

  • Scire, A.; Saccucci, F.; Bertoli, E.; Cambria, M.T.; Principato, G.; D'Auria, S.; Tanfani, F.
    Effect of acidic phospholipids on the structural properties of recombinant cytosolic human glyoxalase II (2002), Proteins, 48, 126-133.
    View publication on PubMed
Search for more literature for 3.1.2.6

Inhibitors

Inhibitors Comment Organism Structure
acidic phospholipids noncompetitive inhibition, lower thermal stability of the enzyme, inhibit protein intermolecular interactions/aggregation by thermal denaturation, small changes in the secondary structure are caused Homo sapiens
anionic phospholipids noncompetitive inhibition, cytosolic isozyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol cytosolic isozyme, soluble Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 purified recombinant cytosolic isozyme
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-D-lactoylglutathione + H2O
-
 Homo sapiens glutathione + D-lactate
-
 ?

Synonyms

Synonyms Comment Organism
acetoacetylglutathione hydrolase
-
 Homo sapiens
Germ cell specific protein
-
 Homo sapiens
GII
-
 Homo sapiens
GLO II
-
 Homo sapiens
glyoxalase II
-
 Homo sapiens
hydrolase, acetoacetylglutathione
-
 Homo sapiens
hydrolase, hydroxyacylglutathione
-
 Homo sapiens
Round spermatid protein RSP29
-
 Homo sapiens
S-2-hydroxylacylglutathione hydrolase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
 assay at Homo sapiens