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Literature summary for 3.1.2.28 extracted from

  • Chen, M.; Ma, X.; Chen, X.; Jiang, M.; Song, H.; Guo, Z.
    Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli (2013), J. Bacteriol., 195, 2768-2775.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.2.28

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0025
-
 1,4-dihydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
0.008
-
 1-hydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
0.0265
-
 3,5-dihydroxybenzoyl-CoA pH 7.0, 25°C Escherichia coli
0.0269
-
 3,4-dihydroxybenzoyl-CoA pH 7.0, 25°C Escherichia coli
0.033
-
 1,4-dihydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
0.073
-
 salicylyl-CoA pH 7.0, 25°C Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A8Y8
-
-
Escherichia coli P77781
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,4-dihydroxy-2-naphthoyl-CoA + H2O
-
 Escherichia coli CoA + 1,4-dihydroxy-2-naphthoate
-
 ?
1-hydroxy-2-naphthoyl-CoA + H2O
-
 Escherichia coli CoA + 1-hydroxy-2-naphthoate
-
 ?
3,4-dihydroxybenzoyl-CoA + H2O
-
 Escherichia coli CoA + 3,4-dihydroxybenzoate
-
 ?
3,5-dihydroxybenzoyl-CoA + H2O
-
 Escherichia coli CoA + 3,5-dihydroxybenzoate
-
 ?
additional information very poor substrate: acetyl-CoA, no substrate: palmitoyl-CoA Escherichia coli ?
-
 ?
salicylyl-CoA + H2O
-
 Escherichia coli CoA + salicylate
-
 ?

Synonyms

Synonyms Comment Organism
EntH
-
 Escherichia coli
YdiI
-
 Escherichia coli

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.13
-
 1,4-dihydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
6.2
-
 1,4-dihydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
12.6
-
 3,5-dihydroxybenzoyl-CoA pH 7.0, 25°C Escherichia coli
14.8
-
 1-hydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
23.2
-
 3,4-dihydroxybenzoyl-CoA pH 7.0, 25°C Escherichia coli
93
-
 salicylyl-CoA pH 7.0, 25°C Escherichia coli

General Information

General Information Comment Organism
physiological function deletion of the 1,4-dihydroxy-2-naphthoyl-coenzyme A hydrolase ydiI gene from the bacterial genome results in a significant decrease in menaquinone production, which is little affected in thioesterases ybgC and entH mutants Escherichia coli

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
400
-
 1,4-dihydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
480
-
 3,5-dihydroxybenzoyl-CoA pH 7.0, 25°C Escherichia coli
860
-
 3,4-dihydroxybenzoyl-CoA pH 7.0, 25°C Escherichia coli
1300
-
 salicylyl-CoA pH 7.0, 25°C Escherichia coli
1900
-
 1-hydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli
2500
-
 1,4-dihydroxy-2-naphthoyl-CoA pH 7.0, 25°C Escherichia coli