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Literature summary for 3.1.2.20 extracted from
- Characterization of acyl-CoA thioesterase activity in isolated rat liver peroxisomes. Partial purification and characterization of a long-chain acyl-CoA thioesterase (1994), Eur. J. Biochem., 222, 803-811.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| di(2-ethylhexyl)phthalate | induces the mitochondrial enzyme by 10fold | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| albumin | - |
Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
| microsome | - |
Rattus norvegicus | - |
- |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| peroxisome | - |
Rattus norvegicus | 5777 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 40000 | - |
1 * 40000, SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| palmitoyl-CoA + H2O | Rattus norvegicus | - |
CoA + palmitate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 260fold | Rattus norvegicus |
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + H2O | - |
Rattus norvegicus | CoA + a carboxylate | - |
? | |
| hexadecanoyl-CoA + H2O | i.e. palmitoyl-CoA | Rattus norvegicus | CoA + hexadecanoate | - |
? | |
| octadecanoyl-CoA + H2O | i.e. stearoyl-CoA | Rattus norvegicus | CoA + octadecanoate | - |
? | |
| palmitoyl-CoA + H2O | - |
Rattus norvegicus | CoA + palmitate | - |
? | |
| propionyl-CoA + H2O | - |
Rattus norvegicus | CoA + propionate | - |
? | |
| tetradecanoyl-CoA + H2O | i.e. myristoyl-CoA | Rattus norvegicus | CoA + tetradecanoate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 40000, SDS-PAGE | Rattus norvegicus |
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Release 2023.1 (January 2023)
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