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Literature summary for 3.1.2.2 extracted from

  • Hunt, M.C.; Greene, S.; Hultenby, K.; Svensson, L.T.; Engberg, S.; Alexson, S.E.
    Alternative exon usage selectively determines both tissue distribution and subcellular localization of the acyl-CoA thioesterase 7 gene products (2007), Cell. Mol. Life Sci., 64, 1558-1570.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol strongly decreased levels of ACOT7 activity and protein in cytosol in patients diagnosed with fatty acid oxidation defects Mus musculus 5829
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mitochondrion strongly decreased levels of ACOT7 activity and protein in mitochondria in patients diagnosed with fatty acid oxidation defects Mus musculus 5739
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Organism

Organism UniProt Comment Textmining
Mus musculus
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SV/129 male and female mice
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Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue brown and white, weak expression of Acot7 in male mice Mus musculus
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brain Acot7 is expressed mainly in brain and testis of male mice. In female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary Mus musculus
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heart moderate expression in male mice. In female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary Mus musculus
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kidney weak expression of Acot7 in male mice Mus musculus
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liver weak expression of Acot7 in male mice Mus musculus
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lung moderate expression in male mice. In female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary Mus musculus
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additional information Acot7 gene is expressed as multiple isoforms in a tissue-specific manner. Expression in tissues other than brain and testis is likely to play important roles in fatty acid metabolism. Identification of five possible first exons in mouse Acot7 (Acot7a–e). All five first exons are transcribed in a tissue-specific manner Mus musculus
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muscle weak expression of Acot7 in male mice Mus musculus
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ovary in female mice, mRNA expression of Acot7 isoforms is highest in brain, lung, kidney, heart and ovary Mus musculus
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spleen weak expression of Acot7 in male mice Mus musculus
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testis Acot7 is expressed mainly in brain and testis of male mice Mus musculus
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Synonyms

Synonyms Comment Organism
Acot7
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Mus musculus
acyl-CoA thioesterase 7
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Mus musculus
brain acyl-CoA hydrolase
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Mus musculus
CTE-II
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Mus musculus
CTE-IIa
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Mus musculus
long chain acyl-CoA thioester hydrolase
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Mus musculus