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Literature summary for 3.1.2.2 extracted from

  • Sakuma, S.; Fujimoto, Y.; Yoshimura, M.; Saeki, K.; Mukai, A.; Akimoto, M.; Fujita, T.
    Effect of 13-hydroperoxyoctadecadienoic acid on the supply of arachidonic acid for prostaglandin synthesis from arachidonoyl-CoA mediated by the cytosolic or microsomal acyl-CoA hydrolase in rabbit kidney medulla (1999), IUBMB Life, 48, 539-542.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
13-hydroperoxyoctadecadienoic acid only the mitochondrial enzyme form is inhibited, not the cytosolic one Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Oryctolagus cuniculus 5829
-
mitochondrion
-
 Oryctolagus cuniculus 5739
-

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
 cytosolic and mitochondrial enzyme forms
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney medulla Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.15
-
 mitochondrial enzyme form, substrate arachidonoyl-CoA Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonoyl-CoA + H2O i.e. all-cis-5,8,11,14-eicosatetranoate Oryctolagus cuniculus CoA + arachidonate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Oryctolagus cuniculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Oryctolagus cuniculus