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Literature summary for 3.1.2.2 extracted from

  • Knauer, T.E.
    Factors affecting the activity and stability of the palmitoyl-coenzyme A hydrolase of rat brain (1979), Biochem. J., 179, 515-523.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.2.2

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoate)
-
 Rattus norvegicus
Hg2+
-
 Rattus norvegicus
Mg2+
-
 Rattus norvegicus
p-hydroxymercuribenzoate
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
 gel filtration Rattus norvegicus
130000
-
 gel filtration, glycerol is included in the eluting buffer Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + H2O Rattus norvegicus
-
 CoA + palmitate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
-50°C over 2 months Rattus norvegicus
0°C, unstable Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + H2O long-chain fatty-acyl-CoA Rattus norvegicus CoA + a carboxylate
-
 ir
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Rattus norvegicus CoA + hexadecanoate
-
 ir
palmitoyl-CoA + H2O
-
 Rattus norvegicus CoA + palmitate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Rattus norvegicus