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Literature summary for 3.1.2.12 extracted from
- Purification and characterization of S-formylglutathione hydrolase from human, rat and fish tissues (1995), Adv. Exp. Med. Biol., 372, 427-434.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.019 | - |
4-methylumbelliferyl acetate | - |
Homo sapiens |  |
| 0.2 | - |
S-formylglutathione | - |
Homo sapiens | |
| 0.49 | - |
4-nitrophenyl acetate | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
2 * 32000, SDS-PAGE | Homo sapiens |
| 53000 | - |
gel filtration | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Lota maculosa | - |
burbot | - |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
| partial | Rattus norvegicus |
| partial | Lota maculosa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 26.9 | - |
- |
Lota maculosa |
| 208 | - |
- |
Rattus norvegicus |
| 3390 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl acetate + H2O | - |
Homo sapiens | 4-methylumbelliferone + acetate | - |
? | |
| 4-methylumbelliferyl acetate + H2O | very low activity | Rattus norvegicus | 4-methylumbelliferone + acetate | - |
? | |
| 4-methylumbelliferyl acetate + H2O | very low activity | Lota maculosa | 4-methylumbelliferone + acetate | - |
? | |
| 4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
| p-nitrophenyl acetate + H2O | very low activity | Rattus norvegicus | p-nitrophenol + acetate | - |
? | |
| p-nitrophenyl acetate + H2O | very low activity | Lota maculosa | p-nitrophenol + acetate | - |
? | |
| S-acetylglutathione + H2O | - |
Homo sapiens | glutathione + acetate | - |
? | |
| S-acetylglutathione + H2O | - |
Rattus norvegicus | glutathione + acetate | - |
? | |
| S-acetylglutathione + H2O | - |
Lota maculosa | glutathione + acetate | - |
? | |
| S-formylglutathione + H2O | - |
Homo sapiens | glutathione + formate | - |
? | |
| S-formylglutathione + H2O | - |
Rattus norvegicus | glutathione + formate | - |
? | |
| S-formylglutathione + H2O | - |
Lota maculosa | glutathione + formate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 32000, SDS-PAGE | Homo sapiens |
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