Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.2.11 extracted from

  • Drummond, G.I.; Stern, J.R.
    Enzymes of ketone body metabolism. II. Properties of an acetoacetate-synthesizing enzyme prepared from ox liver (1960), J. Biol. Chem., 235, 318-325.
    View publication on PubMed
Search for more literature for 3.1.2.11

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol stimulation Bos taurus
alpha-thioglycerol stimulation Bos taurus
beta-mercaptoethylamine stimulation Bos taurus
cysteine stimulation Bos taurus
glutathione stimulation Bos taurus
thioglycolate stimulation Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetoacetyl-CoA + H2O Bos taurus liver ketogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetoacetyl-CoA + H2O
-
 Bos taurus acetoacetate + CoA
-
 ?
acetoacetyl-CoA + H2O liver ketogenesis Bos taurus ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 pH 7.0, 20 min, 79% decrease of specific acitvity Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Bos taurus

pH Range

pH Minimum pH Maximum Comment Organism
6.7 9
-
 Bos taurus