Literature summary for 3.1.13.2 extracted from

Sipova, H.; Springer, T.; Rejman, D.; Simak, O.; Petrova, M.; Novak, P.; Rosenbergova, S.; Pav, O.; Liboska, R.; Barvik, I.; Stepanek, J.; Rosenberg, I.; Homola, J.
5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes (2014), Nucleic Acids Res., 42, 5378-5389.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
DNA-RNA hybrid + H2O	Escherichia coli	-	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
DNA-RNA hybrid + H2O	-	Escherichia coli	?	-	?
additional information	heteroduplexes with 5'-O-methylphosphonate units in the antisense strand exhibit a significant increase in RNase H cleavage activity by up to 3fold in comparison with the natural heteroduplex	Escherichia coli	?	-	?

Synonyms

Synonyms	Comment	Organism
RNase H	-	Escherichia coli

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Release 2023.1 (January 2023)