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Literature summary for 3.1.13.2 extracted from

  • Zhou, D.; Chung, S.; Miller, M.; Grice, S.F.; Wlodawer, A.
    Crystal structures of the reverse transcriptase-associated ribonuclease H domain of xenotropic murine leukemia-virus related virus (2012), J. Struct. Biol., 177, 638-645.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) Codon Plus RIL cells Xenotropic MuLV-related virus

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method, using 40% (w/v) PEG1500, 100 mM Na citrate pH 4.7, and 5 mM MgCl2 Xenotropic MuLV-related virus

Inhibitors

Inhibitors Comment Organism Structure
beta-thujaplicinol
-
Xenotropic MuLV-related virus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ dependent on Xenotropic MuLV-related virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA-RNA hybrid + H2O Xenotropic MuLV-related virus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Xenotropic MuLV-related virus A1Z651
-
-

Purification (Commentary)

Purification (Comment) Organism
His Trap column chromatography, heparin column chromatography, and Superdex 75 gel filtration Xenotropic MuLV-related virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA-RNA hybrid + H2O
-
Xenotropic MuLV-related virus ?
-
?

Synonyms

Synonyms Comment Organism
RNase H
-
Xenotropic MuLV-related virus