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Literature summary for 3.1.13.2 extracted from

  • Lee, J.S.; Hattori, M.; Kim, J.
    Inhibition of HIV-1 protease and RNase H of HIV-1 reverse transcriptase activities by long chain phenols from the sarcotestas of Ginkgo biloba (2008), Planta Med., 74, 532-534.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-hydroxy-6-pentadecylbenzoic acid isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
2-hydroxy-6-[(8Z)-pentadec-8-en-1-yl]benzoic acid isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
2-[(10Z)-heptadec-10-en-1-yl]-6-hydroxybenzoic acid isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
3-pentadecylphenol isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
3-tridecylphenol isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
3-[(10Z)-heptadec-10-en-1-yl]phenol isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
3-[(8Z)-pentadec-8-en-1-yl]phenol isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
5-tridecylbenzene-1,3-diol isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
5-[(8Z)-pentadec-8-en-1-yl]benzene-1,3-diol isolated from the CH2Cl2 extracts of the sacrotestas of Ginkgo biloba Human immunodeficiency virus 1
illimaquinone
-
Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
-
-

Synonyms

Synonyms Comment Organism
RNase H
-
Human immunodeficiency virus 1

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
the IC50 values for 3-[(8Z)-pentadec-8-en-1-yl]phenol, 3-[(10Z)-heptadec-10-en-1-yl]phenol, 3-tridecylphenol, 3-pentadecylphenol, 5-[(8Z)-pentadec-8-en-1-yl]benzene-1,3-diol, and 5-tridecylbenzene-1,3-diol are above 200 microM Human immunodeficiency virus 1 additional information
0.0337
-
-
Human immunodeficiency virus 1 2-hydroxy-6-[(8Z)-pentadec-8-en-1-yl]benzoic acid
0.05
-
-
Human immunodeficiency virus 1 illimaquinone
0.0585
-
-
Human immunodeficiency virus 1 2-[(10Z)-heptadec-10-en-1-yl]-6-hydroxybenzoic acid
0.1703
-
-
Human immunodeficiency virus 1 2-hydroxy-6-pentadecylbenzoic acid