Activating Compound | Comment | Organism | Structure |
---|---|---|---|
AMP | activates, causes conformational changes on some sites of the enzyme N-terminus near strand beta2 and beta3 andhelix alphaA, residues 28-69 | Human immunodeficiency virus 1 |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | backbone and reaction dynamics, kinetics, NMR relaxation study of the isolated RNase H domain, effect of pH on backbone dynamics, different motional models, overview | Human immunodeficiency virus 1 |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | activates, causes conformational changes on some sites of the enzyme N-terminus near strand beta2 and beta3 and helix alphaA, residues 28-69 | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
i.e. HIV-1 | - |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA-RNA hybrid + H2O | - |
Human immunodeficiency virus 1 | ? | - |
? | |
additional information | the enzyme is part of the viral reverse transcriptase, the isolated RNase H domain is inactive at low pH | Human immunodeficiency virus 1 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | the enzyme is part of the viral reverse transcriptase | Human immunodeficiency virus 1 |
ribonuclease H | - |
Human immunodeficiency virus 1 |
RNase H | - |
Human immunodeficiency virus 1 |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.4 | 6.8 | assay at pH 5.4, pH 5.5, and pH 6.8 | Human immunodeficiency virus 1 |