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Literature summary for 3.1.13.1 extracted from

  • Kumagai, H.; Nakamura, M.; Ozaki, N.; Igarashi, K.; Hirose, S.
    Purification and mode of action of a microsomal exoribonuclease from rat liver (1985), Biochim. Biophys. Acta, 827, 431-438.
    View publication on PubMed
Search for more literature for 3.1.13.1

Activating Compound

Activating Compound Comment Organism Structure
spermine stimulating Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
RNA with a terminal 3'-phosphate group on the potential substrate molecule Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
K+ 100 mM KCl stimulating Rattus norvegicus
Mg2+ necessary for activity Rattus norvegicus
Mn2+ can partially replace Mg2+ Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
88000
-
 gel filtration Rattus norvegicus
92000
-
 SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ss RNA + H2O Rattus norvegicus
-
 5'-phosphomononucleotides
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
370fold, nearly to homogeneity Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information 3'-phosphorylated RNA is not hydrolyzed Rattus norvegicus ?
-
 ?
poly(A) + H2O
-
 Rattus norvegicus 5'-AMP + oligonucleotide
-
 ?
ss RNA + H2O
-
 Rattus norvegicus 5'-phosphomononucleotides
-
 ?