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Literature summary for 3.1.11.6 extracted from

  • Chase, J.W.; Richardson, C.C.
    Exonuclease VII of Escherichia coli (1975), Basic Life Sci., 5A, 225-234.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
EDTA can funtion in absence of divalent cations Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
single-stranded DNA + H2O Escherichia coli
-
hydrolyzed single-stranded DNA oligonucleotides ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
xseA
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polydeoxyribonucleotides + H2O
-
Escherichia coli hydrolyzed single-stranded DNA
-
?
single-stranded DNA + H2O
-
Escherichia coli hydrolyzed single-stranded DNA oligonucleotides ?
single-stranded DNA + H2O no endonuclease activity Escherichia coli hydrolyzed single-stranded DNA limit products: oligonucleotides: dimers to dodecamers ?
single-stranded DNA + H2O no activity homopolymers Escherichia coli hydrolyzed single-stranded DNA limit products: oligonucleotides: dimers to dodecamers ?
single-stranded DNA + H2O processive degradation Escherichia coli hydrolyzed single-stranded DNA limit products: oligonucleotides: dimers to dodecamers ?
thymine dimers + H2O possible role in repair of ultraviolet damage Escherichia coli hydrolyzed single-stranded DNA
-
?