Any feedback?
Literature summary for 3.1.11.5 extracted from
- Exonuclease V from Saccharomyces cerevisiae. A 5-3-deoxyribonuclease that produces dinucleotides in a sequential fashion (1988), J. Biol. Chem., 263, 8099-8105.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NaCl | - |
Saccharomyces cerevisiae |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.007 | - |
oligonucleotide (polydT)8 polydA | - |
Saccharomyces cerevisiae |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required, optimal concentration around 3-12 mM | Saccharomyces cerevisiae | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 99000 | - |
sedimentation, calculated | Saccharomyces cerevisiae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| single stranded DNA + H2O | Saccharomyces cerevisiae | - |
5'-phosphomonoester oligonucleotides | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
yeast | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oligonucleotide (polydT)8 polydA + H2O | - |
Saccharomyces cerevisiae | ? | - |
? | |
| single stranded DNA + H2O | - |
Saccharomyces cerevisiae | 5'-phosphomonoester oligonucleotides | - |
? | |
| single stranded DNA + H2O | no endonuclease activity | Saccharomyces cerevisiae | 5'-phosphomonoester oligonucleotides | - |
? | |
| single stranded DNA + H2O | degrades only single stranded DNA from 5'-end | Saccharomyces cerevisiae | 5'-phosphomonoester oligonucleotides | - |
? | |
| single stranded DNA + H2O | not ATP dependent | Saccharomyces cerevisiae | 5'-phosphomonoester oligonucleotides | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
- |
Saccharomyces cerevisiae |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
