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Literature summary for 3.1.11.3 extracted from

  • Sriprakash, K.S.; Lundh, N.; Huh, M.M.O.; Radding, C.M.
    The specificity of lambda exonuclease. Interactions with single-atranded DNA (1975), J. Biol. Chem., 250, 5438-5445.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
double-stranded DNA + H2O Escherichia coli
-
single-stranded DNA + 5'-phospho-2'-deoxynucleotides
-
?
double-stranded DNA + H2O Lambdavirus lambda
-
single-stranded DNA + 5'-phospho-2'-deoxynucleotides
-
?
single-stranded DNA + H2O Escherichia coli at single-stranded DNA branches 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O Lambdavirus lambda at single-stranded DNA branches 5'-phosphomononucleotides
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
Escherichia coli infected with phage lambda only
-
Lambdavirus lambda
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded DNA + H2O
-
Escherichia coli single-stranded DNA + 5'-phospho-2'-deoxynucleotides
-
?
double-stranded DNA + H2O
-
Lambdavirus lambda single-stranded DNA + 5'-phospho-2'-deoxynucleotides
-
?
double-stranded DNA + H2O degrades native DNA 100 times faster than long single-stranded DNA or oligonucleotides Escherichia coli single-stranded DNA + 5'-phospho-2'-deoxynucleotides
-
?
double-stranded DNA + H2O degrades native DNA 100 times faster than long single-stranded DNA or oligonucleotides Lambdavirus lambda single-stranded DNA + 5'-phospho-2'-deoxynucleotides
-
?
single-stranded DNA + H2O degrades the 5'-terminated strand at a single-stranded branch Escherichia coli 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O degrades the 5'-terminated strand at a single-stranded branch Lambdavirus lambda 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O rate of digestion and binding is inversely related to the chain lenght Escherichia coli 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O rate of digestion and binding is inversely related to the chain lenght Lambdavirus lambda 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O digestion not processively Escherichia coli 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O digestion not processively Lambdavirus lambda 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O binds to circular or linear single-stranded DNA Lambdavirus lambda 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O at single-stranded DNA branches Escherichia coli 5'-phosphomononucleotides
-
?
single-stranded DNA + H2O at single-stranded DNA branches Lambdavirus lambda 5'-phosphomononucleotides
-
?