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Literature summary for 3.1.11.1 extracted from

  • Wang, W.; Daley, J.M.; Kwon, Y.; Xue, X.; Krasner, D.S.; Miller, A.S.; Nguyen, K.A.; Williamson, E.A.; Shim, E.Y.; Lee, S.E.; Hromas, R.; Sung, P.
    A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection (2018), J. Biol. Chem., 293, 17061-17069 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.11.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
double stranded DNA containing mismatches + H2O Saccharomyces cerevisiae
-
 ?
-
 ?
additional information Saccharomyces cerevisiae Ku restricts the access of the enzyme to DNA ends. DNA with ends occluded by the DNA end-joining factor Ku70-Ku80 is a suitable substrate for long-range 5'->3' resection when a nick is introduced at a locale proximal to one of the Ku-bound DNA ends ?
-
 ?
nicked circular single stranded DNA containing mismatches + H2O Saccharomyces cerevisiae
-
 ?
-
 ?
nicked double stranded DNA containing mismatches + H2O Saccharomyces cerevisiae
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P39875
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double stranded DNA containing mismatches + H2O
-
 Saccharomyces cerevisiae ?
-
 ?
additional information Ku restricts the access of the enzyme to DNA ends. DNA with ends occluded by the DNA end-joining factor Ku70-Ku80 is a suitable substrate for long-range 5'->3' resection when a nick is introduced at a locale proximal to one of the Ku-bound DNA ends Saccharomyces cerevisiae ?
-
 ?
nicked circular single stranded DNA containing mismatches + H2O
-
 Saccharomyces cerevisiae ?
-
 ?
nicked double stranded DNA containing mismatches + H2O
-
 Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
Exo1
-
 Saccharomyces cerevisiae
exonuclease 1
-
 Saccharomyces cerevisiae