Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.11.1 extracted from

  • Redrejo-Rodriguez, M.; Vigouroux, A.; Mursalimov, A.; Grin, I.; Alili, D.; Koshenov, Z.; Akishev, Z.; Maksimenko, A.; Bissenbaev, A.; Matkarimov, B.; Saparbaev, M.; Ishchenko, A.; Morera, S.
    Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA (2016), Biochimie, 128-129, 20-33 .
    View publication on PubMed
Search for more literature for 3.1.11.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BH110(DE3) cells Bacillus subtilis

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method, using 16% (w/v) PEG 4000, 0.1 M Tris pH 8.5, 0.2 M CaCl2 Bacillus subtilis

Inhibitors

Inhibitors Comment Organism Structure
Zn2+
-
 Bacillus subtilis

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-end 3'-dAMP-labeled (5R,6S)-thymine glycol-thymidine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled (5R,6S)-thymine glycol-thymidine duplex + H2O Bacillus subtilis 168
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 1,N6-ethenoadenine-thymidine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 1,N6-ethenoadenine-thymidine duplex + H2O Bacillus subtilis 168
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrothymine-adenosine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrothymine-adenosine duplex + H2O Bacillus subtilis 168
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrouracil-guanine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrouracil-guanine duplex + H2O Bacillus subtilis 168
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 5-hydroxycytosine-guanine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 5-hydroxycytosine-guanine duplex + H2O Bacillus subtilis 168
-
 ?
-
 ?
3'-end 3'-dAMP-labeled 7,8-dihydro-8-oxoguanine-cytosine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled alpha-anomeric 2'-deoxyadenosine-thymidine duplex + H2O Bacillus subtilis low efficiency ?
-
 ?
3'-end 3'-dAMP-labeled tetrahydrofuran-T duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled uracil-guanine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
3'-end 3'-dAMP-labeled urea-thymidine duplex + H2O Bacillus subtilis
-
 ?
-
 ?
5 mC-G duplex + H2O Bacillus subtilis
-
 ?
-
 ?
5 ohmC-G duplex + H2O Bacillus subtilis
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P37454
-
-
Bacillus subtilis 168 P37454
-
-

Purification (Commentary)

Purification (Comment) Organism
Q-Sepharose column chromatography and HiTrap-heparin column chromatography Bacillus subtilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-end 3'-dAMP-labeled (5R,6S)-thymine glycol-thymidine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled (5R,6S)-thymine glycol-thymidine duplex + H2O
-
 Bacillus subtilis 168 ?
-
 ?
3'-end 3'-dAMP-labeled 1,N6-ethenoadenine-thymidine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled 1,N6-ethenoadenine-thymidine duplex + H2O
-
 Bacillus subtilis 168 ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrothymine-adenosine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrothymine-adenosine duplex + H2O
-
 Bacillus subtilis 168 ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrouracil-guanine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled 5,6-dihydrouracil-guanine duplex + H2O
-
 Bacillus subtilis 168 ?
-
 ?
3'-end 3'-dAMP-labeled 5-hydroxycytosine-guanine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled 5-hydroxycytosine-guanine duplex + H2O
-
 Bacillus subtilis 168 ?
-
 ?
3'-end 3'-dAMP-labeled 7,8-dihydro-8-oxoguanine-cytosine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled alpha-anomeric 2'-deoxyadenosine-thymidine duplex + H2O low efficiency Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled tetrahydrofuran-T duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled uracil-guanine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
3'-end 3'-dAMP-labeled urea-thymidine duplex + H2O
-
 Bacillus subtilis ?
-
 ?
5 mC-G duplex + H2O
-
 Bacillus subtilis ?
-
 ?
5 ohmC-G duplex + H2O
-
 Bacillus subtilis ?
-
 ?

Synonyms

Synonyms Comment Organism
3'->5'exonuclease
-
 Bacillus subtilis
ExoA
-
 Bacillus subtilis