Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(-)-N1-phenethylnorcymserine | - |
Mus musculus | |
(-)-N1-phenethylnorphenserine | - |
Mus musculus | |
(-)-N1-phenethylnorphysostigmine | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (2-phenylethyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (3,4-dimethoxyphenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-acetylphenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-butylphenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-chlorophenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-methoxyphenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-nitrophenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-phenoxyphenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-tert-butylphenyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (cyclohexylmethyl)carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl 1,3-benzodioxol-5-ylcarbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl benzylcarbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl biphenyl-4-ylcarbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl cyclohexylcarbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl hexylcarbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl naphthalen-2-ylcarbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl [4-(dimethylamino)phenyl]carbamate | - |
Mus musculus | |
(3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl [4-(hexyloxy)phenyl]carbamate | - |
Mus musculus | |
physostigmine | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylthiocholine + H2O | - |
Mus musculus | thiocholine + acetate | - |
? | |
butyrylthiocholine + H2O | - |
Mus musculus | thiocholine + butyrate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BuChE | - |
Mus musculus |
butyrylcholinesterase | - |
Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000018 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (cyclohexylmethyl)carbamate | |
0.0000066 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl benzylcarbamate | |
0.00001 | - |
pH not specified in the publication, at 37°C | Mus musculus | (-)-N1-phenethylnorphysostigmine | |
0.000014 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl hexylcarbamate | |
0.000016 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (2-phenylethyl)carbamate | |
0.000022 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl cyclohexylcarbamate | |
0.000079 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl [4-(dimethylamino)phenyl]carbamate | |
0.000083 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-methoxyphenyl)carbamate | |
0.000097 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (3,4-dimethoxyphenyl)carbamate | |
0.0001 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl 1,3-benzodioxol-5-ylcarbamate | |
0.00028 | - |
pH not specified in the publication, at 37°C | Mus musculus | physostigmine | |
0.00034 | - |
pH not specified in the publication, at 37°C | Mus musculus | (-)-N1-phenethylnorphenserine | |
0.00037 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-chlorophenyl)carbamate | |
0.00043 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-tert-butylphenyl)carbamate | |
0.00054 | - |
pH not specified in the publication, at 37°C | Mus musculus | (-)-N1-phenethylnorcymserine | |
0.00058 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl naphthalen-2-ylcarbamate | |
0.00098 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-butylphenyl)carbamate | |
0.0011 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl biphenyl-4-ylcarbamate | |
0.0014 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl [4-(hexyloxy)phenyl]carbamate | |
0.002 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-phenoxyphenyl)carbamate | |
0.0059 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-acetylphenyl)carbamate | |
0.0067 | - |
pH not specified in the publication, at 37°C | Mus musculus | (3aS)-3a,8-dimethyl-1-(2-phenylethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-nitrophenyl)carbamate |