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Literature summary for 3.1.1.8 extracted from

  • Massoulie, J.; Perrier, N.; Noureddine, H.; Liang, D.; Bon, S.
    Old and new questions about cholinesterases (2008), Chem. Biol. Interact., 175, 30-44.
    View publication on PubMed
Search for more literature for 3.1.1.8

Activating Compound

Activating Compound Comment Organism Structure
additional information cancer induces the enzyme Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
gene organization and evolution of cholinesterases Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information mutation of a conserved arginine in neuroligin and BChE induces misfolding and retention in the endoplasmic reticulum Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-
soluble
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens BChE tetramers from human plasma are associated with proline-rich peptides derived froma cytoplasmic protein, lamellipodin or RAPH1. BChE does exert a toxic effect on cultured neurons ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information BChE tetramers from human plasma are associated with proline-rich peptides derived froma cytoplasmic protein, lamellipodin or RAPH1. BChE does exert a toxic effect on cultured neurons Homo sapiens ?
-
 ?
additional information in addition to the hydrolysis of acetylcholine and other esters, acetylcholinesterase and BChE hydrolyze arylacylamides, although at a much lower rate Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
More BChE corresponds to type T subunits and can be functionally anchored by ColQ and PRiMA Homo sapiens
tetramer tetramerization of BChE can be induced by a peptide corresponding to the PRAD of ColQ or by synthetic polyproline Homo sapiens

Synonyms

Synonyms Comment Organism
BChE
-
 Homo sapiens