Literature summary for 3.1.1.8 extracted from

Cengiz, D.; Cokugras, A.N.; Tezcan, E.F.
A new perspective on thermal inactivation kinetics of human serum butyrylcholinesterase (2002), J. Protein Chem., 21, 145-149.

Search for more literature for 3.1.1.8

Inhibitors

Inhibitors	Comment	Organism	Structure
Benzoylcholine	competitive	Homo sapiens
choline	competitive	Homo sapiens
Succinylcholine	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
6600fold	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
butyrylthiocholine + H2O	-	Homo sapiens	thiocholine + butyrate	-	?

Synonyms

Synonyms	Comment	Organism
pseudocholinesterase	-	Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
40	-	incubation for 24 h inactivates the enzyme, 25% loss of activity after 24 h, enzyme can not be reactivated at 4°C	Homo sapiens
45	-	incubation for 24 h converts the enzyme to a stabilized form, enzyme can be reactivated by incubation at 4°C	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0012	-	Succinylcholine	45°C	Homo sapiens
0.0032	-	Benzoylcholine	37°C	Homo sapiens
0.005	-	Succinylcholine	37°C	Homo sapiens
0.007	-	Benzoylcholine	45°C	Homo sapiens
11	-	choline	37°C	Homo sapiens
15.89	-	choline	45°C	Homo sapiens

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Release 2023.1 (January 2023)