Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,5-bis-(4-allyldimethyl-ammoniumphenyl)-pentan-3-one dibromide | BW284c51, a specific inhibitor of AChE | Gambusia yucatana | |
eserine | - |
Gambusia yucatana |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Michaelis-Menten kinetics | Gambusia yucatana | |
2.38 | - |
acetylthiocholine | enzyme from head, pH 7.4, temperature not specified in the publication | Gambusia yucatana | |
5.47 | - |
acetylthiocholine | enzyme from muscle, pH 7.4, temperature not specified in the publication | Gambusia yucatana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | Gambusia yucatana | - |
choline + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gambusia yucatana | - |
from Yucatan Peninsula, Mexico | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
head | - |
Gambusia yucatana | - |
muscle | - |
Gambusia yucatana | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.12024 | - |
pH 7.4, temperature not specified in the publication | Gambusia yucatana |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | - |
Gambusia yucatana | choline + acetate | - |
? | |
acetylthiocholine + H2O | - |
Gambusia yucatana | thiocholine + acetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Gambusia yucatana |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Gambusia yucatana |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00005 | - |
head enzyme, pH 7.4, temperature not specified in the publication | Gambusia yucatana | 1,5-bis-(4-allyldimethyl-ammoniumphenyl)-pentan-3-one dibromide | |
0.00006 | - |
muscle enzyme, pH 7.4, temperature not specified in the publication | Gambusia yucatana | 1,5-bis-(4-allyldimethyl-ammoniumphenyl)-pentan-3-one dibromide | |
0.00022 | - |
head enzyme, pH 7.4, temperature not specified in the publication | Gambusia yucatana | eserine | |
0.00033 | - |
muscle enzyme, pH 7.4, temperature not specified in the publication | Gambusia yucatana | eserine |
General Information | Comment | Organism |
---|---|---|
physiological function | acetylcholinesterase (AChE) is a very important enzyme in the nervous system because it hydrolyzes acetylcholine in synaptic functions. Relationship between cholinesterase activity and total length or sex in wild Gambusia yucatana from different water bodies in the Yucatan Peninsula, Mexiko | Gambusia yucatana |