Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | acetylcholinesterase activity remains unaffected by the two drugs simvastatin and atorvastatin, that reduce brain lathosterol and cholesterol synthesis rate but do not reduce cholesterol levels, overview | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | acetylcholinesterase activity remains unaffected by the two drugs simvastatin and atorvastatin, that reduce brain lathosterol and cholesterol synthesis rate but do not reduce cholesterol levels, overview | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-acetylthiocholine + H2O | detection with 5,5'-dithio-bis-2-nitrobenzoic acid, i.e. DTNB | Rattus norvegicus | acetate + thiocholine | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Rattus norvegicus |