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Literature summary for 3.1.1.7 extracted from
- Purification and characterization of acetylcholinesterase from oriental fruit fly (Bactrocera dorsalis (Hendel)) (Diptera: Tephritidae) (2004), J. Agric. Food Chem., 52, 5340-5346.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| BW284c51 | 0.01 mM, more than 97% inhibition | Bactrocera dorsalis |  |
| eserine | 0.01 mM, more than 97% inhibition | Bactrocera dorsalis | |
| ethopropazine | 0.01 mM, about 57% inhibition | Bactrocera dorsalis | |
| additional information | no substrate inhibition by acetylthiocholine | Bactrocera dorsalis |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.027 | - |
propionylthiocholine | 25°C | Bactrocera dorsalis | |
| 0.088 | - |
acetylthiocholine | 25°C | Bactrocera dorsalis | |
| 0.195 | - |
S-butyrylthiocholine | 25°C | Bactrocera dorsalis | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 61000 | - |
2 * 61000, SDS-PAGE | Bactrocera dorsalis |
| 116000 | - |
PAGE | Bactrocera dorsalis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bactrocera dorsalis | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| additional information | subunits are linked with disulfide bonds | Bactrocera dorsalis |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from Triton X-100 extract | Bactrocera dorsalis |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| head | - |
Bactrocera dorsalis | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 690 | - |
25°C | Bactrocera dorsalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylthiocholine + H2O | - |
Bactrocera dorsalis | thiocholine + acetate | - |
? | |
| propionylthiocholine + H2O | - |
Bactrocera dorsalis | propanoate + thiocholine | - |
? | |
| S-butyrylthiocholine + H2O | - |
Bactrocera dorsalis | thiocholine + butyrate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 61000, SDS-PAGE | Bactrocera dorsalis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Bactrocera dorsalis |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 45 | - |
irreversible deanturation above | Bactrocera dorsalis |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 111 | - |
S-butyrylthiocholine | 25°C | Bactrocera dorsalis | |
| 433 | - |
propionylthiocholine | 25°C | Bactrocera dorsalis | |
| 1616 | - |
acetylthiocholine | 25°C | Bactrocera dorsalis | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Bactrocera dorsalis |
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