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Literature summary for 3.1.1.7 extracted from

  • Tripathi, R.K.; O'Brien, R.D.
    Purification of acetylcholinesterase from house fly brain by affinity chromatography (1977), Biochim. Biophys. Acta, 480, 382-389.
    View publication on PubMed
Search for more literature for 3.1.1.7

General Stability

General Stability Organism
30-50% loss of activity after dialysis and ultrafiltration Musca domestica

Inhibitors

Inhibitors Comment Organism Structure
Trimethyl(p-aminophenyl)ammonium chloride hydrochloride
-
 Musca domestica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
143000
-
 sucrose density gradient centrifugation, light form Musca domestica
306000
-
 sucrose density gradient centrifugation, heavy form Musca domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetylcholine + H2O Musca domestica
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Musca domestica
-
 house-fly, 5 forms
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification glycoprotein Musca domestica

Purification (Commentary)

Purification (Comment) Organism
-
 Musca domestica

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Musca domestica
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
752
-
-
 Musca domestica

Storage Stability

Storage Stability Organism
0°C, 31% loss of activity after 4 months Musca domestica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylcholine + H2O
-
 Musca domestica choline + acetate
-
 ?
acetylcholine + H2O
-
 Musca domestica ?
-
 ?