Cloned (Comment) | Organism |
---|---|
native and mutant forms of FAEES-III cDNA are cloned and expressed in COS-7 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C39W | mutation does not affect FAEES activity | Homo sapiens |
G32Q | mutation does not affect FAEES activity | Homo sapiens |
H72S | mutation does not affect FAEES activity, less than 9% of control glutathione S-transferase activity | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26000 | - |
x * 26000, FAEES-III, immunoblot analysis | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | FAEES-III metabolizes both ethanol and carcinogens | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
FAEES-III | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
a long-chain-fatty-acyl ethyl ester + H2O = a long-chain-fatty acid + ethanol | mechanism | Homo sapiens |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0006 | - |
native FAEES-III and mutants G32Q, C39W, H72S | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fatty acid + ethanol | - |
Homo sapiens | fatty acyl ethyl ester + H2O | - |
? | |
additional information | FAEES-III also catalyzes the glutathione S-transferase reaction | Homo sapiens | ? | - |
? | |
additional information | FAEES-III metabolizes both ethanol and carcinogens | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 26000, FAEES-III, immunoblot analysis | Homo sapiens |