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Literature summary for 3.1.1.55 extracted from

  • Gresner, P.; Dolnik, M.; Waczulikova, I.; Bryszewska, M.; Sikurova, L.; Watala, C.
    Increased blood plasma hydrolysis of acetylsalicylic acid in type 2 diabetic patients: a role of plasma esterases (2006), Biochim. Biophys. Acta, 1760, 207-215.
    View publication on PubMed
Search for more literature for 3.1.1.55

Application

Application Comment Organism
medicine higher aspirin esterase activity contributes to the lowered response of diabetic platelets to aspirin-mediated antiplatelet therapy Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
4-bis-nitrophenyl phosphate
-
 Homo sapiens
eserine selective for aspirin esterase II Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetylsalicylate + H2O Homo sapiens
-
 salicylate + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens
-
 diabetes 2 patients and healthy individuals, higher activity in diabetes patients than in control individuals at pH 7.4, no differences at pH 5.5
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
-
blood higher aspirin esterase activity contributes to the lowered response of diabetic platelets to aspirin-mediated antiplatelet therapy Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylsalicylate + H2O
-
 Homo sapiens salicylate + acetate
-
 ?

Synonyms

Synonyms Comment Organism
aspirin esterase
-
 Homo sapiens
aspirin esterase I albumin Homo sapiens
aspirin esterase II butyrylcholinesterase Homo sapiens